Chemistry & Biochemistry

Curriculum Vitae

• A.B., Hanover College, 1943;
• Ph.D., University of Illinois 1946;
• Postdoctoral Research Associate, MIT
• Research Chemist, DuPont Company, 1948-1955;
• Professor, Case Western University Department of Chemistry, 1955-1968;
• Professor, University of Wisconsin-Milwaukee Department of Chemistry, 1968-1987.

Research Interests

• Mechanisms of drugs and toxins
• Electron transfer
• Reactive oxygen species
• Oxidative stress
• Cell signaling
• Bioelectrochemistry
• Metabolism of drugs and toxins

Recent Publications

1. Kovacic, Peter; Somanathan, Ratnasamy Toxicity of imine-​iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects Journal of Applied Toxicology (2014), 34, 825-834.
2. Kovacic, Peter; Somanathan, Ratnasamy Unifying effectors of circadian rhythm: Protein N-acetylation, phosphorylation, sulfation and other electrical effects Journal of Electrostatics (2014), 72, 198-202.
3. Kovacic, Peter; Somanathan, Ratnasamy Nitroaromatic compounds: Environmental toxicity, carcinogenicity, mutagenicity, therapy and mechanism Applied Toxicology (2014), 34, 810-824.
4. Kovacic, Peter; Somanathan, Ratnasamy Multifaceted Approach to Circadian Rhythm: Redox, Oxidative Stress, Melatonin, Antioxidants, Nitric Oxide, Hypoxia, Anesthetics, Cortisol and Cocaine Current Chemical Biology (2013), 7, 271-281.
5. Kovacic, Peter; Ott, Nadia; Cooksy, Andrew L. Benzodiazepines: electron affinity, receptors and cell signaling - a multifaceted approach Receptors and Signal Transduction (2013), 33, 338-343.
6. Kovacic, Peter; Somanathan, Ratnasamy Nanoparticles: toxicity, radicals, electron transfer, and antioxidants Methods in Molecular Biology (New York, NY, United States) (2013), 1028(Oxidative Stress and Nanotechnology), 15-35.
7. Kovacic, Peter; Somanathan, Ratnasamy Cell signaling, receptors, electrical effects and therapy in circadian rhythm Journal of Receptors and Signal Transduction (2013), 33, 267-275.
8. Kovacic, Peter; Somanathan, Ratnasamy Sugar Toxicity -- Fundamental Molecular Mechanisms: α-Dicarbonyl, Electron Transfer, and Radicals Journal of Carbohydrate Chemistry (2013), 32, 105-119.